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标题: 疫苗对老年人预防死亡有效性 [打印本页]

作者: 老财迷    时间: 2022-3-20 22:27
标题: 疫苗对老年人预防死亡有效性
看到观察者网转载的文章:柳叶刀:中国生物灭活疫苗对老年人预防死亡有效率为85%
【据中国生物官方微信号“中国生物”3月20日消息,3月15日,阿根廷国家流行病学和国家战略信息局局长Analía Rearte在国际权威医学期刊《柳叶刀》(《The Lancet》)发表新冠疫苗真实世界研究文章,揭示了三款疫苗的效果,其中包括国药集团中国生物新冠灭活疫苗(BBIBP-CorV)。
研究显示,对于60岁及以上的老年人,接种两剂国药中国生物新冠灭活疫苗后,对减少死亡风险的有效率为85%。】
好奇啊,另外两款是啥啊?

去找了一下原文:
Effectiveness of rAd26-rAd5, ChAdOx1 nCoV-19, and BBIBP-CorV vaccines for risk of infection with SARS-CoV-2 and death due to COVID-19 in people older than 60 years in Argentina: a test-negative, case-control, and retrospective longitudinal study
Findings
From Jan 31, to Sept 14, 2021, 1 282 928 individuals were included, of whom 687 167 (53·6%) were in the rAd26-rAd5 analysis, 358 431 (27·6%) in the ChAdOx1 nCoV-19 analysis, and 237 330 (18·5%) in the BBIBP-CorV analysis. Vaccine effectiveness after two doses was high for all three vaccines, adjusted odds ratio 0·36 (95% CI 0·35–0·37) for rAd26-rAd5, 0·32 (0·31–0·33) for ChAdOx1 nCoV-19, and 0·56 (0·55–0·58) for BBIBP-CorV. After two doses, the effect on deaths was higher than that on risk of infection: adjusted hazard ratio 0·19 (95% CI 0·18–0·21) for rAd26-rAd5, 0·20 (0·18–0·22) for ChAdOx1 nCoV-19, and 0·27 (0·25–0·29) for BBIBP-CorV. The indirectly estimated effectiveness on deaths was 93·1% (95% CI 92·6–93·5) for rAd26-rAd5, 93·7% (93·2–94·3) for ChAdOx1 nCoV-19, and 85·0% (84·0–86·0) for BBIBP-CorV following two doses. First dose effect of viral vector vaccines remained stable over time.

Until September, 2021, in Argentina, COVID-19 vaccines developed in non-replicative virus platforms were authorised and widely used in people older than 60 years: rAd26-rAd5 (Sputnik V), ChAdOx1 nCoV-19 (Oxford–AstraZeneca), and the inactivated vaccine BBIBP-CorV (Sinopharm). The administration of vaccines to people older than 60 years began in January, 2021, with rAd26-rAd5 V and ChAdOx1 nCoV-19 used from February, 2021; BBIBP-CorV was used from March, 2021.
3款分别是rAd26-rAd5 (Sputnik V), ChAdOx1 nCoV-19 (Oxford–AstraZeneca), and the inactivated vaccine BBIBP-CorV (Sinopharm).
没有美国的mRNA,可能是当初产量不足,没给阿根廷?
这研究的时间段,奥密克戎变种还没出来,也不知道这数据对现在的状况有多少指导意义。

哪位大神有空看下给我们说几句


作者: 史节    时间: 2022-3-22 22:40
本帖最后由 史节 于 2022-3-22 23:05 编辑

港大今天发布的数据是三针科兴和三针复必太在60岁以上老人身上的避免死亡的有效性都差不多,98%。

2022年3月22日的 庄时利和的评论




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